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Paenidigyamycin G

Inoculation, fermentation, extraction (MeOH & CH2Cl2), Kupchan, semi-preparative HPLC

Molecular Formula
C15H19N2O+
Melting Point
-
Colour & Text
UGCHKK015
Location of Source
IC50 (anti-leishmanial activity) = 115.41 ug/mL
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Legonoxamine A

Inoculation, fermentation, extraction(MeOH), fractionation (SPE column), semi-preparative HPLC.

Molecular Formula
C31H52N6O8
Melting Point
-
Colour & Text
UGCHKK031
Location of Source
-
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(2R,3R)-1-phenylbutane-2,3-diol

Inoculation, Fermentation, Solid Phase Extraction, Molecular Network analysis of fractions, Disc diffusion assay, and HPLC.

Molecular Formula
C10H14O2
Melting Point
-
Colour & Text
UGCHKK030
Location of Source
Poor inhibitory activity against C. albicans ATCC
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Fasamycin C

Inoculation, fermentation, extraction (MeOH), fractionation using silica gel 60, and HPLC-UV Analysis.

Molecular Formula
C28H24O7
Melting Point
-
Colour & Text
UGCHKK026
Location of Source
MIC(S. aureus ATCC25923) = 6.30, MIC(E. faecalis A
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2β-hydroxy-3-oxo-D:A-friedooleanan-30-oic acid

Molecular Formula
C29H46O4
Melting Point
-
Colour & Text
UGCHIA015
Location of Source
-

Molecular Formula
C29H46O4
Melting Point
-
Colour & Text
UGCHIA015
Location of Source
-
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Euscaphic acid

Column chromatography and purified using Sephadex LH-20 column.

Molecular Formula
C30H48O5
Melting Point
270-271
Colour & Text
KNUSTPHBH004
Location of Source
IC50 (amylase) = 215 uM
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Arjunolic acid

The ethanol extract was partitioned, and the ethyl acetate fraction was subjected to silica gel column and further purified using Sephadex LH-20 column

Molecular Formula
C30H48O5
Melting Point
-
Colour & Text
KNUSTPHBH007
Location of Source
IC50 (amylase) = 151.90 uM and EC50 (glucose uptake in C2C12 myotubes) = 24.21 uM
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Dichapetalin A

Extraction by percolation using acetone, column chromatography and preparative HPLC.

Molecular Formula
C38H48O5
Melting Point
211-214 oC
Colour & Text
UGCHIA038
Location of Source
Good antibacterial activity
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Wisaninic acid

The compound was isolated from the petroleum ether fraction of the roots of Piper guineenses

Molecular Formula
C13H12O5
Melting Point
221-224
Colour & Text
UGCHIA008
Location of Source
-
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1,2-dihydro-7-deacetoxy-7-oxogedunin

Cold maceration, column chromatography and semi-preparative HPLC.

Molecular Formula
C26H34O5
Melting Point
-
Colour & Text
KNUSTCHEM009
Location of Source
IC50(Anti-inflammatory activity) = 31.01 uM and IC
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